LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression
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چکیده
منابع مشابه
1,25(OH)2D3 inhibits the progression of hepatocellular carcinoma via downregulating HDAC2 and upregulating P21(WAFI/CIP1).
Vitamin D, termed 1,25(OH)2D3 in it's active form, activity is associated with a reduced risk of hepatocellular carcinoma (HCC) and is an important immune regulator. However, the detail molecular mechanisms underlying the effects of 1,25(OH)2D3 on the progression of HCC are widely unknown. Histone deacetwylase 2 (HDAC2) is usually expressed at high levels in tumors, and its downregulation leads...
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ژورنال
عنوان ژورنال: Molecular Therapy - Oncolytics
سال: 2020
ISSN: 2372-7705
DOI: 10.1016/j.omto.2020.10.013